Vitamin D aids the clearing out of old cells (autophagy) – many studies

autophagy = aa TAH fuh jee

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Vitamin D in autophagy signaling for health and diseases: Jan 2022

Insights on potential mechanisms and future perspectives FREE PDF

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Vitamin D in Autophagy Signaling for Health and Diseases: – Aug 2021

Insights on Potential Mechanisms and Future Perspectives
J Nutr Biochem. 2021 Aug 14;108841. doi: 10.1016/j.jnutbio.2021.108841 PDF is behind a paywall
Sujit K Bhutia 1

Vitamin D regulates the pleiotropic effect to maintain cellular homeostasis and epidemiological evidence establishes an association between vitamin D deficiency and various human diseases. Here, the role of autophagy, the cellular self-degradation process, in vitamin D-dependent function is documented in different cellular settings and discussed the molecular aspects for treating chronic inflammatory, infectious diseases, and cancer. Vitamin D activates autophagy through a genomic and non-genomic signaling pathway to influence a wide variety of physiological functions of different body organs along with bone health and calcium metabolism. Moreover, it induces autophagy as a protective mechanism to inhibit oxidative stress and apoptosis to regulate cell proliferation, differentiation, and immune modulation. Furthermore, vitamin D and its receptor regulate autophagy signaling to control inflammation and host immunity by activating antimicrobial defense mechanisms. Vitamin D has been revealed as a potent anticancer agent and induces autophagy to increase the response to radiation and chemotherapeutic drugs for potential cancer therapy. Increasing vitamin D levels in the human body through timely exposure to sunlight or vitamin D supplements could activate autophagy as part of the homeostasis mechanism to prevent multiple human diseases and aging-associated dysfunctions.

Table of Contents

2. Vitamin D, biosynthesis, and receptor
3. Autophagy: the self-degradative mechanism
4. Vitamin D, vitamin D receptor, and autophagy signaling
5. Vitamin D in health and diseases: the role of autophagy
5.1. Vitamin D-induced autophagy in maintaining cellular homeostasis
5.1.1. Skin and vitamin D: the complex relationship
5.1.2. Maintaining healthy bone, periodontal health, and muscle function
5.1.3. Heart and blood vessel abnormalities
5.1.4. Nervous system and neurological disorder
5.1.5. Gastrointestinal system and gut microbiome
5.1.6. Liver and inflammation
5.1.7. Pancreas, kidney, and diabetes pathogenesis
5.1.8. Lungs and pulmonary diseases
5.1.9. Ovary and gynecological disorder
5.2. Vitamin D-induced lethal autophagy controls cellular transformation and cancer
5.3. Vitamin D-induced autophagy in immunity and infection
5.4. Vitamin D, Autophagy, and aging: Does it have a role in controlling COVID-19?
6. Conclusion and future perspectives

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Vitamin D-Cathelicidin Axis: at the Crossroads between Protective Immunity and Pathological Inflammation during Infection - 2020

 Download the PDF from VitaminDWiki

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Autophagy and Vitamin D Videos

Enhance Autophagy with This ONE Vitamin!: Dr.Berg - 2 minute Video - May 2019

YouTube

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Can Vitamin D Improve Your Fasting Results? - 2022

Dr. Mindy Pelz 10 minutes, need > 50 ng of Vitamin D
she had many videos on fasting for weight loss for women

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The Incredible Benefits Of VITAMIN D For Weight Loss & Burning Body Fat - April 2023?

Dr. Mindy Pelz 8 minutes

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See also VitaminDWiki

VitaminDWiki - Fasting may reduce inflammation and long-COVID - June 2023

VitaminDWiki - Longevity experts take Vitamin D, Omega-3, and Magnesium - Patrick video Sept 2023

"Autophagy" occurs >500 times in VitaminDWiki - mainly in PDFs

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Vitamin D reduces COVID-19 complications – June 2021

• Vitamin D reduces COVID-19 complications – June 2021
  • Vitamin D attenuates COVID-19 complications via modulation of proinflammatory cytokines, antiviral proteins, and autophagy
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Immunity category in VitaminDWiki

273 items in Immunity category

    see also

Virus category listing has 1401 items along with related searches

Overview Influenza and vitamin D
Vitamin D helps both the innate and adaptive immune systems fight COVID-19 – Jan 2022
Vitamin D aids the clearing out of old cells (autophagy) – many studies
600,000 IU of Vitamin D (total) allowed previously weak immune systems to fight off a virus antigen - Nov 2020
Search for treg OR "t-cell" in VitaminDWiki 1440 items as of Jan 2020
228 VitaminDWiki pages contained "infection" in title (June 2024)
Search VitaminDWik for BACTERIA in title 25 items as of Aug 2019
Vitamin D and the Immune System – chapter Aug 2019
7X less risk of influenza if Vitamin D levels higher than 30 ng – Oct 2017
Common cold prevented and treated by Vitamin D, Vitamin C, Zinc, and Echinacea – review April 2018
Vitamin D improves T Cell immunity – RCT Feb 2016
Immune system - great 11-minute animated video - Aug 2021
   Only the brain is more complex, nothing about Vitamin D
18 titles in VitaminDWiki contained INNATE or ADAPTIVE as of Jan 2023
Increasing publications on vitamin D and Infection

52 studies are in both Immunity and Virus categories

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3+ VitaminDWiki pages with AUTOPHAGY in title

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